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EurekaE/e'ureka: Echo Reading
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Strain tracking

ViewThree apical views at reduced sector width including only the ventricles, true apex visualized, speckle tracking of the full wall.
TimingZero strain at mitral valve closure (end-diastole), end-systole at aortic valve closure; in AF average several cycles or use the third of three similar cycles.
Caliper / traceRegion of interest covering the full myocardial wall only, drawn straight along the long axis; tracking checked against the underlying motion and loops recorded.
Example
Schematic myocardial wall outlines comparing a region of interest matching the wall with one that includes pericardium.
ROI should cover the full wall only. (Schematic drawing (E/e′ureka), not a patient image)

Correct example

Tracking is inspected segment by segment against the visible myocardial motion; poorly tracked segments are excluded, and if more than three segments are uninterpretable GLS is not reported; serial studies use the same vendor and software.

Common error

Accepting smoothed curves without checking tracking, an ROI that includes pericardium or only a subendocardial layer, foreshortened apical views, or event timing that does not match valve closure.

Effect on interpretation

A wide ROI underestimates strain, a narrow one overestimates it, and foreshortening inflates apical values; because serial change is judged in absolute strain, these errors can mimic or mask a 15% relative deterioration.

Why

GLS is the averaged Lagrangian shortening of the wall across the apical views; speckle tracking regularization can smooth over failed tracking, so visual verification is the only safeguard.